GC-biased gene conversion drives accelerated evolution of ultraconserved elements in mammalian and avian genomes

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Figure 2.
Figure 2.

UCE characteristics. (A) Genomic distribution of mUCEs and aUCEs. (B) Number of UCEs that were 100% identical to the ancestor when different numbers of mammalian branches were considered. The pie chart shows the proportion of UCEs when different branches were included. (C) Numbers of homologous sequences of mUCEs present in different vertebrate taxa. (D) Enrichment of human SNPs and counts of divergent sites between humans and chimpanzees in UCEs and randomly selected genomic regions (RANDs). (E) Tissue-specific expression index (τ) of UCE-adjacent genes and RAND-adjacent genes. (F) Gene expression diversity value (CV) of UCE-adjacent genes and RAND-adjacent genes.

This Article

  1. Genome Res. 33: 1673-1689

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