Figure 5.
Nucleosome occupancy, histone modifications, and DNA methylation around CTCF sites. (A) Averaged DNA methylation and nucleosome occupancy profiles around CTCF motifs are bound by CTCF both in NBC and CLL. (B) Same as panel A but for sites bound by CTCF in NBC but not in CLL. (C) Histone modifications around the same set of lost CTCF sites depicted in panel B. The profiles were averaged over all NBCs (black), M-CLL (red), and U-CLL (blue) samples. Standard errors are shown for each line in light colors. The number of regions (N) is indicated on the graph
