Dynamic regulation of gonadal transposon control across the lifespan of the naturally short-lived African turquoise killifish

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Figure 4.
Figure 4.

TE expression dynamics in the aging turquoise killifish gonad. (A) Scheme for TE transcriptional analysis in aging gonads. TE DGE was conducted similar to genic DGE analysis (see Methods) and labeled with nomenclature from Figure 2A. (B) Proportion of reads assigned to TEs from each library. Significance in nonparametric Wilcoxon rank-sum test. (C) Heatmaps of mRNA expression for TEs significantly regulated with age in aging killifish ovaries by DESeq2 LRT (FDR < 10−6). TE family color-coded for each row. (D) Heatmaps of mRNA expression for TEs significantly regulated with age in aging killifish testes by DESeq2 LRT (FDR < 10−6).

This Article

  1. Published in Advance December 28, 2022, doi: 10.1101/gr.277301.122 Genome Res. 33: 141-153

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