Scalable and model-free detection of spatial patterns and colocalization

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Figure 6.
Figure 6.

Extension of SpaGene to identify ligand–receptor interactions. (A) Visualization of IGFBP5-CAV1 and APOE-LRP6 interactions for ST MOB data, with adjusted P-values from SpaGene. (B) Visualization of the PSAP-GPR37L1 interaction for Slide-seqV2 mouse cerebellum data, with the adjusted P-value from SpaGene. Left is the relative expression of the ligand and the receptor; right is the interaction strength.

This Article

  1. Published in Advance September 9, 2022, doi: 10.1101/gr.276851.122 Genome Res. 32: 1736-1745

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