Identification of a transcriptional signature found in multiple models of ASD and related disorders

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Figure 1.
Figure 1.

System for comparison of gene expression profiles of chromatin modifiers. (A) Primary neuronal culture system used to analyze gene expression changes after knockdown of ASD-linked chromatin modifiers. (B–F) Expression of chromatin modifiers following knockdown, from RNA sequencing data. (G) Number of genes down- and up-regulated by knockdown of five ASD-linked chromatin-associated genes. N = 3 replicates.

This Article

  1. Published in Advance September 14, 2022, doi: 10.1101/gr.276591.122 Genome Res. 32: 1642-1654

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