Figure 1.
Overview of the PAC pipeline. (A) A schematic describing the main steps, features, and outputs of PAC. (B) Correlation of reference allele ratios (RARs) between the three different methods (standard alignment, WASP-filtered alignment, PAC) and the ground truth data. Genome-wide Pearson correlation coefficients (R2) are shown (P < 0.05 for all comparisons). (C) Site-level summary statistics for the different analysis methods. Statistics are reported for sites with at least 20× coverage in all three methods. Panel A was created with BioRender (https://biorender.com).
