Cell cycle arrest explains the observed bulk 3D genomic alterations in response to long-term heat shock in K562 cells

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Figure 5.
Figure 5.

Cell cycle redistribution after LHS contributes to observed Hi-C contact map changes. (A) Representative images showing cell cycle phase in sorted G2/M cells for the three conditions. (B) Estimated cell fractions of G1/S- and G2/M-phase cells in mixed cells before and after HS calculated from different chromosomes. (C) Schematic diagram shows the main discoveries of our study.

This Article

  1. Published in Advance July 14, 2022, doi: 10.1101/gr.276554.122 Genome Res. 32: 1285-1297

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