
Reverse correlation of ASVs within the same genus. (A) Granulicatella adiacens versus Granulicatella elegans. (B) Haemophilus parainfluenzae versus Haemophilus. (C) Neisseria versus Neisseria. (D) Streptococcus versus Streptococcus. (Left) Trace plots. The relative abundance of each ASV was scaled to [0,1]. (Middle) Scatter plots. The Spearman's correlation coefficient and P-value were shown in the upper right corner. (Right) Box plots displaying the relative abundance of negatively correlated ASV pairs in different oral sites. Tongue-specific ASVs are blue-colored and plaque-specific ASVs are orange-colored in trace and box plots.











