Snake venom gene expression is coordinated by novel regulatory architecture and the integration of multiple co-opted vertebrate pathways

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Figure 9.
Figure 9.

Model of venom regulatory network. (A) Hypothesis regulatory network that controls venom regulation through high-level regulatory action of ERK signaling. Red arrows indicate enhancer–promoter interactions. (B) Illustration of hypothesized positive-feedback loop in which venom production activates the UPR, which in turn increases venom production through up-regulation and binding of UPR TFs that target VGs (red arrows).

This Article

  1. Published in Advance June 1, 2022, doi: 10.1101/gr.276251.121 Genome Res. 32: 1058-1073

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