Snake venom gene expression is coordinated by novel regulatory architecture and the integration of multiple co-opted vertebrate pathways

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 1.
Figure 1.

Venom gene (VG) expression and structure in the prairie rattlesnake. (A) Proportions of venom protein components in prairie rattlesnake venom (adapted from Schield et al. 2019). (B) Structure of tandemly duplicated VG families, with genes colored by relative gene expression at 1DPE. Relative expression is scaled separately per family to accentuate expression variation within families. (C) VGs with significant up-regulation in the 1DPE venom gland (DESeq2 log2foldChange > 0 and IHW-corrected P-value < 0.05) compared with expression in all nonvenom tissues (stomach, pancreas, and liver).

This Article

  1. Published in Advance June 1, 2022, doi: 10.1101/gr.276251.121 Genome Res. 32: 1058-1073

Preprint Server



Current Issue

  1. February 2026, 36 (2)
  1. Current Issue
  1. Alert me to new issues of Genome Research