
Genes are interrupted by introns that must be accurately spliced from messenger RNA precursors. In this issue, the nucleotide composition of the genome is shown to directly contribute to splicing efficiency in Paramecium. The artwork depicts the genome of the ciliated unicellular organism Paramecium, inspired by the cut-paper collages of Henri Matisse's Jazz artbook. (Cover illustration by Eve Charmant, Instagram @evecharmant, eve.charmant{at}gmail.com. [For details, see Gnan et al., pp. 699–709.])