Figure 5.
Analysis of reporter effect on nearby endogenous gene expression. (A) Schematic of DECAL analysis framework. (B,C) Rate of significant effect on gene expression by whether reporter and gene are in the same TAD (B) and whether reporter is inside or outside gene body (C). Numbers at the top indicate the number of significant tests. Error bars represent 99% confidence intervals estimated by 1000 bootstrap simulations. (D) Significant tests for each category broken down by proportion of those that increase versus decrease expression.
