Functional noncoding SNPs in human endothelial cells fine-map vascular trait associations

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Figure 5.
Figure 5.

IL1B treatment trends with molQTLs and motif mutations. (A) Diagram of treatment design and Venn diagram of SNPs that validated in untreated (left), IL1B-treated for 6 h (right), and IL1B-treated for 24 h (bottom). (B) Heat map of enrichment scores comparing SNPs uniquely in specific treatment conditions between STARR-seq and the molQTLs (i.e., SNPs only significant in STARR-seq 0-h and not in 6-h or 24-h IL1B-treated). (C) Heat map of enrichment scores comparing SNPs uniquely in specific treatment conditions between STARR-seq and the motif mutations.

This Article

  1. Genome Res. 32: 409-424

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