Analyzing rare mutations in metagenomes assembled using long and accurate reads

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Figure 1.
Figure 1.

strainFlye pipeline. Given a metagenome assembly of HiFi reads, strainFlye identifies rare mutations in each MAG, estimates their FDR, performs phasing analyses using these mutations, identifies hotspots and coldspots of mutations, produces MAG-specific codon and amino acid mutation matrices, and computes information about MAGs’ growth dynamics.

This Article

  1. Published in Advance November 23, 2022, doi: 10.1101/gr.276917.122 Genome Res. 32: 2119-2133

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