Fast and accurate mapping of long reads to complete genome assemblies with VerityMap

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Figure 2.
Figure 2.

Alignments of reads from the Cen9Sim data set to Cen9del10 generated by minimap2, Winnowmap2, and VerityMap shown using the Integrative Genomics Viewer (IGV) browser (Robinson et al. 2011). minimap2 does not report any primary alignments (shown in gray) spanning the deletion breakpoint, and all secondary alignments (shown in white) indicate systematic mismatches mapping to an incorrect copy of the repeat. Winnowmap2 reports mappings that are incorrectly spanning the breakpoint. VerityMap either reports an alignment correctly spanning the deletion breakpoint (indicates a 10-kb deletion) or clips read alignment at the breakpoint.

This Article

  1. Published in Advance November 15, 2022, doi: 10.1101/gr.276871.122 Genome Res. 32: 2107-2118

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