Figure 5.
Targeted Methyl-SNP-seq. (A) Pairwise comparison of the methylation level of CpG islands measured by targeted Methyl-SNP-seq, whole-genome Methyl-SNP-seq (WGS Methyl-SNP-seq), whole-genome bisulfite sequencing by ENCODE (WGBS), and Nanopore sequencing. Only CpG islands having coverage ≥ 50 were used for correlation calculation. (B) Two allele-specific methylations (ASMs) depicted by targeted Methyl-SNP-seq. Only Cs in CpG context are shown. Coordinates on the x-axis correspond to positions on Chr X (left) and Chr 11 (right) (GRCh38).
