Figure 4.
Differentially methylated genomic regions (DMRs). (A) Chr 2: A known example of allele-specific methylation. The reads having different alleles of the arrow-pointed heterozygous SNP site are labeled with blue (REF SNP) and red (ALT SNP). SNP: rs11686156. (B) Chr 20: 10-kb upstream of GNAS-AS1 gene and overlapping reported DMRs (Fang et al. 2012). (C) Chr X: XIST. (D) Chr X: PDK3. (E) MBTPS2. Only Cs in the CpG context are shown. Coordinates on the x-axis correspond to positions on respective chromosomes (GRCh38 assembly).
