Figure 5.
Recurrent mtDNA deletion patterns emerge in nonrespiring lines. The left part of each heatmap shows the normalized depth of coverage of short-read sequencing libraries on the reference mtDNA sequence, grouped by mtDNA features. The right part of each heatmap shows the growth AUC in the four conditions tested. Rows represent individual MA lines (including initial and final time points). Lines are hierarchically clustered by depth of coverage profile similarity. The top lines represent the parental strains.
