Figure 4.
CTCF displays contrasting diversity in fly and human. (A–C) cisDIVERSITY identifies 17 motifs and 13 modules in the fly CTCF data. Motif 1 shown in a red box is the canonical fly CTCF motif. (D–F) cisDIVERSITY identifies only six motifs and six modules in the human CTCF data. Again, motif 1 in the red box matches the canonical vertebrate CTCF motif. Motifs 2–5 resemble the vertebrate CTCF but differ at one of three parts denoted with dotted lines. These motifs are shown with 10-bp flanks to ensure that they are genuine variants of the motif.
