
Spontaneous mutation rates per haploid genome per generation in relation to temperature of the MAL experiment. Top: Mutation rate of the total sum of de novo mutations. Bottom: Separate mutation rates of single nucleotide mutations (SNMs) and single nucleotide indels (SNIs). Nonlinear fit as second-order polynomial regression; R² values are given to describe the goodness of model fit. Corresponding test statistics are listed in Supplemental Data 2.











