Transcriptional milestones in Dictyostelium development

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Figure 4.
Figure 4.

Transcriptional milestones mark developmental transitions. The heatmaps show the mRNA abundance in the indicated 19 strains, in which each row represents a gene, and each column represents expression data averaged across the multiple samples annotated with a common majority stage in the strain. The yellow-blue colors represent relative mRNA abundances (relative expression scale on the right). Stage transitions are indicated on the left. The genes are ordered based on the direction of their regulation patterns (blue, down; yellow, up). Phenotype groups, strain names, and annotated morphological stages are indicated above the heatmap blocks. The phenotype groups are wild type (WT, light blue), precocious development (precocious, violet), small fruiting body (sFB, dark blue), culmination defective (cul defective, dark green), tight-aggregate arrest (tag, dark yellow), tight-aggregate/loose-aggregate disaggregation (disagg, orange), and aggregationless (agg-, red). The morphological stage color represents the majority morphology as indicated in the legend on the right: no aggregation (no_agg, red), rippling/stream (ripple, brown), loose aggregate (lag, orange), tight aggregate (tag, dark yellow), tipped aggregate (tip, light green), slug/first finger (slug, dark green), Mexican hat (Mhat, jade green), culmination (cul, cyan), fruiting body (FB, light blue), and yellow mound (yem, dark gray).

This Article

  1. Genome Res. 31: 1498-1511

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