Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

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Figure 4.
Figure 4.

Alu divergence level effects strand asymmetry. From the Johnson et al. data, the genome-wide median RMC (y-axis) for each annotated Alu consensus position (x-axis) is plotted for Reference (Ref)- or Complement (Comp)-oriented Alu insertions, grouped by levels of divergence (indicated in respective colors) measured by milliDiv units (e.g., <100 corresponds to <10% divergence from the ancestral consensus; see Methods). The gray bands represent two standard deviations from the median. The black arrow indicates the start of the A-tail sequence.

This Article

  1. Genome Res. 31: 866-876

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