Figure 2.
Clustering of MPRA signal by strand. Hierarchical clustering of Spearman's correlation coefficients is shown for MPRA signal from (A) a pooled BAC-derived STARR-seq library spanning HTT gene in four cell types, (B) a whole-genome-derived STARR-seq library in A549 cells from Johnson et al., and (C) whole-genome libraries from four donors in a promoter-less reporter system with an upstream test element in two cell types from Van Arensbergen et al. All comparisons were made from binned data (see Methods).
