Copy number variation underlies complex phenotypes in domestic dog breeds and other canids

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Figure 3.
Figure 3.

Instances of CNVs associated with phenotypes overlapping chromatin contacts. (A,B) Hi-C interaction heat maps for significant contacts on Chromosomes 26 and 9. The white squares on the x-axis mark the position the GWAS hits. The arrows mark the position and directionality of the most significant CTCF motifs of the area. The dashed circles within the Hi-C plot mark the significant interactions involving the relevant genes and the associated CNVs.

This Article

  1. Published in Advance April 16, 2021, doi: 10.1101/gr.266049.120 Genome Res. 31: 762-774

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