Copy number variation underlies complex phenotypes in domestic dog breeds and other canids

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Figure 1.
Figure 1.

Global and specific differences in CN between breed dogs, village dogs, and wolves. (A) Copy number-based principal component analysis of breed dogs (orange), village dogs (green), and wolves (purple). (B,C) Depictions of the copy number values for two highly differentiated loci: the HBB chain gene cluster (ENSCAFT00000009978, ENSCAFT00000022860, ENSCAFT00000009984) and SLIT2. Discrete copy number values for all samples are depicted in rectangle plots. Purple: wolves, green: village dogs, orange: modern dogs. Top panel: VST values for the same genomic windows; bottom panel: copy number window values.

This Article

  1. Published in Advance April 16, 2021, doi: 10.1101/gr.266049.120 Genome Res. 31: 762-774

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