Usage of promoters across bovine tissues. (A) Correlation between pairs of alternative TSCs from the same gene (>5 CPM). Alternative TSCs were generally independent from each other. (B) Usage of TSCs across tissues. Most of the TSCs were expressed in only one or a few tissues, whereas about 6000 TSCs were ubiquitously expressed. (C) Use of alternative TSCs between pairs of tissues. Sphere size represents the number of TSC members in the module, and edge thickness represents the number of common genes expressed from alternative (tissue-specific) TSCs. (D,E) Examples of tissue-specific promoters in brain and testis. The GABRG2 and GABRA1 genes are members of the GABAergic synapse pathway.
