Dynamic genomic landscape of polyploid strains. The polyploid genomes of the three subpopulations beer, wine 1, and teq/EtOH underlie massive modifications through LOH events. The primary genome (low genetic variation) was used as a reference. Conserved patterns of modified regions for the primary genome were identified by determining the gain or loss of its copies in each strain, here varying between three (3×) and zero (0×). Only a few modified regions are unique to single or few strains. There are no common regions that show the same patterns across subpopulations. The teq/EtOH subpopulation shows a division into two clusters, each consisting of three individuals. The ploidy level was estimated in 10-kb windows.
