Epstein–Barr virus nuclear antigen 2 extensively rewires the human chromatin landscape at autoimmune risk loci

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Figure 4.
Figure 4.

EBNA2-dependent alteration of the human chromatin landscape. (A) EBNA2 binding and EBNA2-dependent chromatin opening at the promoter of the up-regulated EBNA2 DEG NAALADL2-AS2, the most up-regulated EBNA2 DEG (UCSC Genome Browser screenshot [hg19]). (B,C) EBNA2-dependent alteration of chromatin looping at the SLAMF1 locus. (B) EBNA2-dependent looping to the promoter of the EBNA2 DEG SLAMF1. Loops outside the window are not shown. (C) Extensive EBNA2-dependent rewiring of the chromatin looping landscape at the SLAMF1 locus.

This Article

  1. Published in Advance November 19, 2021, doi: 10.1101/gr.264705.120 Genome Res. 31: 2185-2198

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