Epstein–Barr virus nuclear antigen 2 extensively rewires the human chromatin landscape at autoimmune risk loci

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Figure 2.
Figure 2.

Differential gene expression in EBV-infected Ramos cells. Venn diagrams depicting the number of up-regulated genes (A) and down-regulated genes (B) based on comparisons between EBVEBNA2+ versus uninfected and EBVEBNA2− versus uninfected conditions, respectively. Heatmaps depict genes that are specifically expressed higher (C) or lower (D) in EBVEBNA2+ cells. Values in the heatmaps indicate the normalized relative Z-score of the FPKMs across each row (i.e., the default normalization method in the R “heatmap” function) (R Core Team 2021).

This Article

  1. Genome Res. 31: 2185-2198

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