Model depicting distribution of chromatin regulators across a trypanosome polycistronic transcription unit. Diagram shows the five Class I (sharp; green) and 10 Class II (broad; purple) TSR-associated factors at a unidirectional/single RNAPII promoter. The arrow indicates the direction of transcription. The gray rectangle represents a single polycistron. Class II proteins are enriched in the direction of transcription. The eight proteins found at RNAPII TTRs associated with RNAPIII-transcribed genes are shown in blue. tRNA and snRNA genes are represented by the brown rectangle. Proteins within each box were found to interact in the proteomic experiments.
