Cancer-associated dynamics and potential regulators of intronic polyadenylation revealed by IPAFinder using standard RNA-seq data

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Figure 6.
Figure 6.

Comparison between IPAFinder and APAlyzer. (A) Venn diagram illustrating the overlap of up-regulated IpA events upon HNRNPC-KD identified by IPAFinder and APAlyzer, respectively. (B) Representative RNA-seq tracks for genes with increased IpA usage inferred by IPAFinder but not APAlyzer. (C) Sequence flanking three IPA sites shown in B have (U)5 tract (red) and poly(A) signal (blue). The first bases of skipped terminal exons are denoted by enlarged characters.

This Article

  1. Published in Advance September 2, 2021, doi: 10.1101/gr.271627.120 Genome Res. 31: 2095-2106

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