Mutational bias in spermatogonia impacts the anatomy of regulatory sites in the human genome

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Figure 5.
Figure 5.

Elevated singleton insertion rates at PRDM9 and NRF1 binding sites contrast with other short variant classes. All gnomAD variants have been down-sampled to a total of 650,000 variants per analysis, making the y-axes directly comparable; individual bins are 5 bp in size. Only regions around TFBSs with ≥95% unique mappability (umap24 scores) were included.

This Article

  1. Published in Advance August 20, 2021, doi: 10.1101/gr.275407.121 Genome Res. 31: 1994-2007

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