Subclustering of neurons reveals finer structure that distinguishes different types of neurons. (A) Cells with reads in peaks near genes with expression patterns specific to neuron subtypes cluster together (bbs-8: ciliated sensory neurons; gcy-32: oxygen sensory neurons; unc-30: GABA-ergic neurons; mec-7: touch receptor neurons; ceh-24: cholinergic neurons). (B) Cells in the UMAP plot are colored by the number of marker genes with nearby coaccessible peaks. Here, we show marker genes for the ASE neurons, a specific pair of ciliated sensory neurons, which are identified in one of the bbs-8 clusters from A (marked by the left-facing arrow), and show marker genes shared by the oxygen sensory neurons AQR, PQR, and URX, which further support the cluster marked with gcy-32 in A (marked by the right-facing arrow).
