Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development

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Figure 1.
Figure 1.

De novo identification of editing sites in adult neurons. (A) The adult neural editing sites identified were cross-referenced with previously reported sites to identify novel editing sites. (B) Genomic distribution of adult neural sites. (CDS) Coding region; (UTR) untranslated region; (ncRNA) noncoding RNA. (C) A Two Sample Logo analysis of editing sites identified in adult neural cells compared with adenosines present in the same dsRNA region. Enriched and depleted nucleotides are shown above and below the axis, respectively. The level of conservation is represented by letter height. Logos were generated using a Student's t-test with P < 0.05 and no Bonferroni correction.

This Article

  1. Genome Res. 31: 27-39

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