Reconstruction of clone- and haplotype-specific cancer genome karyotypes from bulk tumor samples

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Figure 3.
Figure 3.

Comparison of RCK and ReMixT on heterogeneous prostate cancer samples. (A) Length-weighted segment copy number distances between segment copy numbers from HATCHet and segment copy numbers output by ReMixT and RCK. (B) Fractions of novel adjacencies from input that are inferred to be present by ReMixT or RCK for each sample in the heterogeneous group. RCK used segment copy numbers from HATCHet in input and novel adjacency utilization parameter P = 1.0, 0.9, 0.75, 0.5.

This Article

  1. Published in Advance September 4, 2020, doi: 10.1101/gr.256701.119 Genome Res. 30: 1274-1290

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