Peiyong Jiang; Tingting Xie; Spencer C. Ding; Ze Zhou; Suk Hang Cheng; Rebecca W.Y. Chan; Wing-Shan Lee; Wenlei Peng; John Wong; Vincent W.S. Wong; Henry L.Y. Chan; Stephen L. Chan; Liona C.Y. Poon; Tak Y. Leung; K.C. Allen Chan; Rossa W.K. Chiu; Y.M. Dennis Lo

Detection and characterization of jagged ends of double-stranded DNA in plasma

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Figure 8.

Diagnostic performance. (A) Jaggedness indices across healthy control subjects (CTR), patients infected with chronic hepatitis B virus (HBV), and patients with hepatocellular carcinoma (HCC). The y-axis indicates the jaggedness index based on the filling of unmethylated cytosine (JI-U). (B) ROC of jaggedness index between subjects with and without HCC.