Figure 3.
Jagged ends in plasma DNA of pregnant women. (A) The profile of JI-U across different sizes of plasma DNA fragments, ranging from 50 bp to 600 bp. (B) The JI-U between shared DNA molecules (mainly of maternal origin) and fetal-specific DNA molecules without size selection. (C) The JI-U between shared DNA molecules and fetal-specific DNA molecules within a range of 130 to 160 bp. (D) JI-U across different sizes for shared and fetal-specific plasma DNA molecules. The JI-U represents the jagged index deduced from unmethylated signals at CG sites.
