Figure 4.
ADARB1-mediated filamin, alpha (Flna) pre-mRNA editing causes intron retention. (A) RNA-seq coverage profile of Flna locus at exon 42-exon 43 from WT, Adar KO, and Adarb1 KO cortices. The editing site is shown at exon 42. (B,C) Linear regression of co-occurrence analysis comparing editing levels and splicing levels of Flna in Adar KO (B) and Adarb1 KO (C) cortex. WT samples are shown in blue and KO samples are shown in red.
