Figure 3.
Relationship between evolutionary conservation of sAUG and fdAUG contexts. TIESS scores for conserved strong and weak sAUG codons and corresponding fdAUG codons. Although distribution of TIESS is indistinguishable for strong sAUGs and their fdAUGs (red histograms), contexts of weak sAUG with in-frame fdAUGs are more conserved than weak sAUG with out-of-frame fdAUGs (top blue histograms). At the same time there are more conservatively weak contexts for out-of-frame fdAUGs than for in-frame fdAUGs among mRNAs with weak sAUGs (left histograms).
