Independent evolution of transcript abundance and gene regulatory dynamics

CHA1 expression is species- and condition-dependent. (A) CHA1 dynamic regulation is varying in trans. Scatters of coexpression vectors of the indicated comparisons, similar to Figure 5A. (B) CHA1 is down-regulated on nitrogen depletion in S. cerevisiae but not in S. paradoxus. Log₂-transformed expression levels of CHA1 in the indicated species and conditions are shown. Expression data of all strains (deletion strains and WT) that were sampled in the indicated conditions are presented. (C) CHA1 expression is reduced upon CHA4 deletion in S. cerevisiae but not in S. paradoxus. Log₂ fold change values (cha4Δ/WT) in gene expression of CHA1 in the indicated conditions are presented.