
The shared genome constrains expression evolution of sex-biased genes in the Drosophila brain. Correlations between male and female expression levels for sex-biased genes in D. melanogaster. For each category (on the y-axis), a Pearson correlation coefficient (x-axis) was calculated for each gene using six male–female data points (one for each strain). The median correlations for each class of sex-biased gene are nonzero. One-sample Wilcoxon signed-rank test P-values <2.2 × 10−16 for each class (female autosomal, female X, male autosomal, and male X). Sex-biased genes are defined in D. melanogaster at an FDR of 0.05.











