
Chromosomal distributions of genes with sex-biased expression in the Drosophila brain. Sex-biased genes are significantly enriched on the X Chromosome and depleted on the autosomes in the three Drosophila species. The red points indicate the observed number of sex-biased genes on a given chromosome arm (at an FDR of 0.05), and the box plots indicate the simulated numbers of sex-biased genes. (*****) P-value <1 × 10−5; (****) P-value <1 × 10−4; (***) P-value <1 × 10−3; (**) P-value <1 × 10−2; (*) P-value < 5 × 10−2. The P-values shown are two times the fraction of simulations, which resulted in a more extreme number of sex-biased genes on a given chromosome arm.











