Single-cell analysis of human embryos reveals diverse patterns of aneuploidy and mosaicism

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Figure 2.
Figure 2.

Aneuploidies discovered in scRNA-seq data from human preimplantation embryos (Petropoulos et al. 2016). (A) Proportions of aneuploid chromosomes, cells, and embryos detected at varying false discovery rates (FDR). Error rates were controlled while accounting for the hierarchical dependency structure of the data (chromosomes within cells within embryos) using TreeBH (Bogomolov et al. 2017). (B) Distribution of proportions of aneuploid cells per embryo at a 1% FDR.

This Article

  1. Genome Res. 30: 814-825

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