Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types

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Figure 4.
Figure 4.

Discovery of SBS_AnT in publicly available mutation data. Example spectra of tumors positive for SBS_AnT. The right panel shows the transcriptional strand bias; for the whole-genome samples, only SBSs in transcribed regions were included. The bile duct, bladder, and HNSCC tumors are whole-exome data; the prostate and rectal tumors are whole-genome data. (U) Untranscribed strand; (T) transcribed strand.

This Article

  1. Published in Advance July 6, 2020, doi: 10.1101/gr.255620.119 Genome Res. 30: 803-813

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