MEDEA: analysis of transcription factor binding motifs in accessible chromatin

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 5.
Figure 5.

Clustering analysis of MEDEA enriched motifs in ENCODE data sets reveals the TF regulatory patterns behind cellular differentiation. 2D-hierarchical clustering of the MEDEA AUROC values for the high pool (Fig. 4A, center). Black frames within the heatmap outline examples of enriched motifs within the indicated phenotypes. Colored bars to the top of the heatmap show how six representative cell type classes (top right) are distributed upon clustering.

This Article

  1. Genome Res. 30: 736-748

Preprint Server