Figure 5.
Core regulatory modules extracted from gene regulatory networks are supported by subpopulation from single-cell RNA-seq data. (A) Heatmap of reordered normalized TRS scores at D2 to D20. The black line represents the detected modules from NMF. (B) Heatmap of D4 normalized TRS on selected specific genes and TFs. (C) Mean expression pattern of genes from three different modules of RA D4 on the developmental stage of seven tissues. (D) Mean expression pattern of genes from three different modules of RA D4 on RA time course. (E) Distribution of RA D4 top 500 module-specific genes’ maximum expressed subpopulations from single-cell RNA-seq data.
