RETrace: simultaneous retrospective lineage tracing and methylation profiling of single cells

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Figure 5.
Figure 5.

RETrace methylation analysis of U87MG and brain single cells. (A) Pairwise dissimilarity between each U87MG ex vivo single cells and ENCODE reference cell line data. (B) Comparison of RETrace-processed cortical neuronal and nonneuronal nuclei and previously published excitatory and inhibitory neuronal subtypes accurately separate NeuN+ and NeuN− nuclei. (C) Similar separation between neuronal and nonneuronal nuclei when analyzing the whole RETrace brain data set.

This Article

  1. Published in Advance March 3, 2020, doi: 10.1101/gr.255851.119 Genome Res. 30: 602-610

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