Analysis of Hi-C data using SIP effectively identifies loops in organisms from C. elegans to mammals

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Figure 1.
Figure 1.

Overview of SIP. (A) The graphical user interface provides options to specify a Juicer-derived .hic file or processed data, the output directory, and chromosome size file. It also allows adjustment of the various parameters shown. (B) SIP uses image-based detection to create a long list of candidate loops, which is further filtered based on properties of the distance-normalized matrix.

This Article

  1. Published in Advance March 3, 2020, doi: 10.1101/gr.257832.119 Genome Res. 30: 447-458

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