Systems genetics of the Drosophila metabolome

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Figure 12.
Figure 12.

Metabolome-based predictions of organismal traits for females (A) and males (B). We used the elastic net regularization and leave-one-out cross-validation to enrich metabolites and predict phenotypic values. Prediction accuracy is estimated as the correlation between predicted and actual values. The blue, red, and green bars, respectively, represent models with training sets of metabolites and module PCs combined, or metabolites and PCs separately.

This Article

  1. Genome Res. 30: 392-405

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