A HOTAIR regulatory element modulates glioma cell sensitivity to temozolomide through long-range regulation of multiple target genes

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Figure 2.
Figure 2.

Intra- and inter-chromosomal interactions with the HOTAIR regulatory element. (A) The 723-bp Capture Hi-C bait region and Capture Hi-C signal near the bait region. (B) Circos plot showing genome-wide intra-interactions indicated by curves extending from the bait region; the two biological replicates are in red and blue, respectively. HOTAIR RE: HOTAIR regulatory element. (C) Circos plot showing genome-wide intra- and inter-interactions indicated by curves extending from the bait region; the two biological replicates are in red and blue, respectively. HOTAIR RE: HOTAIR regulatory element.

This Article

  1. Genome Res. 30: 155-163

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